Management Team

Dr. Julianne Smith
Chief Development Officer

Dr. Smaragda Angelidou
Head of CMC

Julianne Smith
Chief Development Officer
Julianne Smith is Chief Development Officer of Genespire. She has over 30 years of experience in scientific research, with 18 of those working in the biotech industry. She joins Genespire from Nasdaq listed Cellectis S.A., a global leader in gene editing and allogeneic CAR-T cells, where she held various senior roles, managing research teams responsible for the development of allogenic CAR T-cell products, working on product portfolio prioritization and shaping development strategies. While at Cellectis, Julianne also established and led the translational sciences department and interacted with regulatory authorities in both the US and Europe. Julianne holds a PhD in Genetics and Development from Columbia University and pursued her academic career as a Post-Doctoral Fellow at the Institut Curie in Paris.

Dr. Smaragda Angelidou
Head of CMC
Smaragda Angelidou is the Head of CMC of Genespire. She is a CMC subject matter expert with extensive industry experience in cell and gene therapies, from early phase development through to commercialisation. She joined Genespire from Autolus, a clinical stage autologous CAR T-cell therapy company, where she was the Senior Director of CMC projects and Tech Transfer. Prior to Autolus, she worked at GlaxoSmithKline, where she held positions in Cell and Gene Therapy Product Development and Medicine and Process Delivery. She was accountable for the strategic, technical, quality and regulatory aspects of CMC development and previously she was a process development technical lead. In her roles, she worked on a number of CGT programs, including autologous TCR T-cell therapies for cancer and ex vivo HSPC gene therapies for rare diseases, which included Strimvelis, the first approved ex vivo autologous gene therapy. Smaragda holds a BSc in Human Genetics and an MSc in Molecular Medicine from University College, London and a PhD in Molecular Oncology from Imperial College, London.